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Pellagra a review exploring causes and mechanisms, including isoniazid-induced pellagra

For example, cadmium can affect the BLC-2 family of proteins involved in mitochondrial death via the overexpression of antiapoptotic Bcl-2 and the suppression of proapoptotic (BAX, BAK) mechanisms, thus increasing the resistance of various cells to undergo malignant transformation

doi: 10.1002/jcp.27306 272

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