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Walton and Monte 2015), Autism Diagnosis Interview-Revised (ADI-R) (Traglia et al

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All studies were double-blinded RCTs, four of which adequately described the random sequence generation process [10, 18, 19, 21]

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Univariate statistical testing using two-sample t-tests with confirmation by Wilcoxon rank-sum tests identified four metabolitescoumarin, L-leucine, L-octanoylcarnitine, and kaempferolthat differed significantly between ASD and control groups after FDR correction, with large effect sizes (Supplementary Table S2)