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SLE it thought to arise as a consequence of genetic and environmental factors

10.1016/j.trsl.2022.08.006 8 AthaudaD.MaclaganK.SkeneS

1a) has the best effect on promoting the synthesis of GSH and enhancing the activity of glutathione S transferase (GST) 22

Cancer cells produce more spatially concentrated ROS than normal cells, which hyperactivates the cell signaling pathways required for cellular transformation and carcinogenesis (Figure 2)

Importantly, patients may intentionally conceal testosterone use due to a lack of trust in medical personnel, further complicating diagnosis and management