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47 LiuX.ZhaoX.ZengX.BossersK.SwaabD

Lactic acid bacteria: inhibition of angiotensin converting enzyme in vitro and in vivo

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doi:10.12659/msm.882125 Sarkar R, Yadav V, Yadav T, P J, Mandal I

[PMC free article: PMC1894911] [PubMed: 15900287] (In human volunteer studies, kava showed moderate inhibition of CYP 2E1 activity [40%] but no effect on CYP 1A2, 2D6 or 3A4, despite evidence in vitro that kava inhibits these isoenzymes

This could lead to the prediction of future escape variants and the design of vaccine antigens that encode structural epitopes that are more difficult to escape