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References Clark, J

Mitochondria-targeted analogues of metformin exhibit enhanced antiproliferative and radiosensitizing effects in pancreatic cancer cells

doi: 10.1111/jgh.12073, 29

Many show promising early research, clear biological effects, and growing interest in areas such as recovery, body composition, libido, and skin repair

Joint pain developing after starting B12 may reflect: Pre-existing musculoskeletal conditions becoming more noticeable Concurrent inflammatory or degenerative joint disease Reactions to excipients in certain formulations The natural course of an underlying condition If you experience persistent or worsening joint symptoms after beginning B12 supplementation, it is advisable to consult your GP or healthcare provider

Co-Immunoprecipitation Co-immunoprecipitation was performed using Invitrogen TM Dynabeads TM M-270 Epoxy beads (ThermoFisher Scientific) bound to anti-BNIP3-antibody 1C8 or anti-BAX antibody (2D2, Cell Signaling Technologies) (according to the manufacturers instructions (Invitrogen TM Dynabeads TM Co-Immunoprecipitation Kit, ThermoFisher Scientific)