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Reports also describe shrinkage of adipocyte size and reductions in fat-pad mass while preserving insulin signaling markers in certain models
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doi: 10.1046/j.1524-475X.11.s2.1.x
The study demonstrated elevated pain thresholds following DSIP administration in the hot plate test, particularly during the dark phase, and the effect was not blocked by naloxone, indicating a non-opioid analgesic mechanism
