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T., Sjoholm, A

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International Journal of Eating Disorders

Chronic GLP-1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the Kras(G12D) mouse model

Similarly, reducing dietary intake specifically of the amino acid methionine reduces insulin, IGF-1, oxidative stress, and inflammation, and reduces tumor growth in animal models (5254)