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Biochim Biophys Acta Mol Basis Dis

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52 In a phase 1b trial done to evaluate the safety, pharmacokinetics and pharmacodynamics of orforglipron in patients with T2DM, orforglipron resulted in significant reductions in HbA1c, fasting blood glucose and body weight, with an adverse event profile consistent with that of other GLP-1RA

A miRNA expression profiling in both sporadic GH-secreting pituitary adenomas and non-functioning pituitary adenomas highlighted that miR-107, a miRNA involved in many cancer types, was described to be upregulated