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Description
Ferroptosis: The emerging player in remodeling triple-negative breast cancer

IFN- secreted by anti-PD-L1 immunotherapy-activated CD8 + T cells markedly down-regulates SLC3A2 and SLC7A11 expression in tumor cells through the JAK1-STAT1 signaling pathway (SLC3A2 and SLC7A11 are the two subunits that constitute the cystine/glutamate antiporter, known as System Xc ), resulting in reduced cysteine uptake, compromised GPX-4 function, altered mitochondrial activity, heightened lipid peroxidation, and ultimately ferroptosis induction [17, 25]

Some ITCs demonstrate a hormetic effect, offering cytoprotective benefits at low doses and cytotoxic, antitumor properties at higher doses (149, 150)

Antimicrobial Nanoarchitectonics

Each bar is crafted to create a rich, luxurious lather that rinses away easily, making your bathing experience both indulgent and efficient

Hussain M
