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No obvious conserved features in the recognition of sterol ligands are observed for these GPCRs and SRD5A2, suggesting highly diverse mechanisms of sterol ligand recognition by membrane proteins

& Reiter, E

Emerging efforts to evaluate the role of the susceptibility loci for pulmonary fibrosis have led to unexpected results, as demonstrated by the discovery of the association of MUC5B variant with disease risk, but improved disease prognosis
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"WATER II Trial (Aquablation)"