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study highlighted the dysregulation of glutathione metabolism in septic patients and emphasized that the impaired biosynthetic response may contribute to heightened oxidative damage and worsened clinical outcomes (Liu et al., 2024)

Multidrug resistance proteins (MRPs, ABCCs): Importance for pathophysiology and drug therapy

This matrix is composed of ceramides, cholesterol, and free fatty acids, such as linoleic acid (linoleate), palmitic acid (palmitate), and oleic acid (oleate), which contribute to the skins structural stability, water retention, and defense against microbial penetration [7,8]

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[PubMed: 1830732] 37