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Elevated plasma vitamin B12 in patients with hepatic glycogen storage diseases

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10.1016/j.jep.2024.118850 103 LiuY.RaffertyT

Cagrilintide + Tirzepatide Storage & Handling Storage Reference (Both Compounds) State Lyophilized (long-term) Tirzepatide -4 F (-20 C), 12+ months Cagrilintide -4 F (-20 C), 12+ months State Lyophilized (short-term) Tirzepatide 35.6-46.4 F (2-8 C), several months Cagrilintide 35.6-46.4 F (2-8 C), several months State Reconstituted (liquid) Tirzepatide 35.6-46.4 F (2-8 C), 28-30 days Cagrilintide 35.6-46.4 F (2-8 C), 28-30 days State Color when reconstituted Tirzepatide Clear, colorless Cagrilintide Clear, colorless State Shake

Acetic Acid Water (0.1%) is the recommended first-step solvent for lyophilised peptides that do not dissolve cleanly in neutral water including many growth hormone-related peptides, IGF family peptides, GHRP-family peptides, and melanocortin analogues

Pharmacokinetics and toxicology of therapeutic proteins: Advances and challenges :advances and challenges