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Global Burden of Disease Study 2019 (GBD 2019) Healthcare Access and Quality Index 1990-2019 (Seattle, United States of America: Institute for Health Metrics and Evaluation, 2022)

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Of note, the obtained evidence is complete (i.e., monocrotaline-treated rats develop significant pulmonary hypertension and marked RVe hypertrophy

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At the present time, early screening -with biomarker panels or a liver ultrasound, ideally with transient elastography- is reserved for high-risk patients (i.e., obese patients with T2DM or elevated plasma AST/ALT levels or evidence of steatosis at a random liver exam) until more accurate non-invasive methods are available

Nonalcoholic steatohepatitis: summary of an AASLD single topic conference