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This could be a protective negative feedback loop to prevent energy utilization getting out of hand if the insulin signal is too strong
Metformin is a first-line drug for treating type 2 diabetes associated with AMPK activation
However, if you experience vomiting within 3 hours of taking an oral contraceptive pill or severe diarrhoea lasting more than 24 hours, follow the missed pill guidance in your patient information leaflet
The dose may be increased to 1.5 mg once weekly to achieve glycemic control
