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As these neutrophils squeeze between the cells, they release HOCl, which can react with GSH secreted from the epithelial cells that normally protects the epithelial cells (Venglarik et al., 2003)

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The accumulation of advanced glycation end products (AGEs) can also induce apoptosis (cell death) in fibroblasts, resulting in a significant loss of hyaluronic acid, collagen, and elastin

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Randomized double-blind clinical trial examining the Ellagic acid effects on glycemic status, insulin resistance, antioxidant, and inflammatory factors in patients with type 2 diabetes