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doi: 10.1089/bari.2017.0008

Dihexa acts as a small-molecule HGF mimetic, occupying the same receptor binding site but with three-fold higher affinity than endogenous HGF in rodent hippocampal assays

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The alkylating chemotherapeutic temozolomide induces metabolic stress in IDH1-mutant cancers and potentiates NAD(+) depletion-mediated cytotoxicity