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Recently new cis- Trans derivatives of hydrazides have been synthesized and found to possess anti-inflammatory and anti-microbial activity

10.1016/S1570-0232(03)00399-4 Summary Keywords acetaminophen, reactive metabolite, covalent binding, glutathione S -transferase, bottom-up proteomics, data-dependent acquisition, high-resolution tandem mass spectrometry, multiple reaction monitoring Citation Geib T, Lento C, Wilson DJ and Sleno L (2019) Liquid Chromatography-Tandem Mass Spectrometry Analysis of Acetaminophen Covalent Binding to Glutathione S -Transferases

Preliminary experiments indicated that this IMF digesta was not toxic to intestinal cells (% of viability = 99.56 2.95, MTS assay, Supplementary Figure 5)

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