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People dealing with high stress, mental fatigue, or slower recovery notice better effects with NAD+
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Singap Med J
Li X., Kwon N., Guo T., Liu Z., Yoon J., Angew
ATP depletion secondary to mitochondrial dysfunction further limits PMCA turnover, establishing a reciprocal cycle in which impaired extrusion promotes mitochondrial Ca 2+ overload, which in turn worsens energetic insufficiency and ROS production (Millington-Burgess and Harper, 2021)
