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(122) have shown that by encapsulating BDNF, NPs can provide controlled and sustained release, which may enhance the therapeutic efficacy and reduce the frequency of administration

This difference in reactivity between EITC and PITC can again be explained using the computational results shown in Fig

(2013), who reported decreased mGlu 2 mRNA levels in the prefrontal cortex of alcohol-dependent rats (Meinhardt et al., 2013)

They also demonstrated significant modulation of genes related to glucose metabolism and changes in gut microbiota, revealing distinct in vivo behaviours of FX and FZ linked to their digestion rates (Zhang, Dong et al

The primary outcome measure in these studies was change in depressive symptoms, which were assessed using validated depression rating scales such as: Hamilton Depression Rating Scale (HDRS) Beck Depression Inventory (BDI) Montgomery-sberg Depression Rating Scale (MADRS) Some trials also measured anxiety using the Hamilton Anxiety Rating Scale (HARS)
