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Finally, crosstalk between the IGF axis and signaling via the ER [133] or AR [134] can promote treatment resistance by stimulating hormone-receptor-dependent transcriptional pathways

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Based on the primary analysis and exposureresponse results from the DREAMM-2 study, belantamab mafodotin received accelerated approval from the FDA for the treatment of patients with triple-refractory multiple myeloma and 4 prior lines of therapy

[DOI] [PMC free article] [PubMed] [Google Scholar] 49.Tuttle KR, Lakshmanan MC, Rayner B, et al

HoutkooperRHMouchiroudLRyuDMoullanNKatsyubaEKnottGet al

doi: 10.1073/pnas.2219585120
