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These small (12 kDa) redox enzymes catalyse not only the reduction of disulfides, but also the reduction of mixed disulfides, in a process called deglutathionylation

Utine CA, Li G, Asbell P, Pflugfelder S, Akpek E

Theranostics 11 , 78447868 (2021)

Kumar, A., & Loane, D

3.1 Clinical studies of ferroptosis in neurodegenerative diseases Human biospecimen analyses revealed elevated agrin expression, reduced levels of platelet-derived growth factor receptor beta (PDGFR), type IV collagen, and fibronectin, pronounced small artery atherosclerosis and venous collagen deposition, and a reduction in pericyte numbers in the brain tissue of AD patients