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However, single-target RTKs have been proven to be inefficient due to multiple factors, such as the negative feedback activation in other oncogenic pathways [49] and the existence of complex crosstalks between different RTK pathways [12]

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These are summarised, together with the studies from which they were reported and the peptides measured, in electronic supplementary material (ESM) section Protein Selection and ESM Tables 1, 2

Dimeric mimetic of BDNF loop 4 promotes survival of serum-deprived cell through TrkB-dependent apoptosis suppression

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