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Straus DJ, Andreeff M , Hansen HJ, Mertelsmann R, Koziner B, Chaganti R, Gee TS, McKenzie S, Melamed MR, Clarkson BD

Intraoral melanoacanthoma: a reactive melanocytic hyperplasia

An increased exposure to sunlight will increase the production of melanin tremendously
Because MPNSTs may grow aggressively, local invasion into surrounding tissues such as bone, muscle, or organs can lead to secondary symptoms like swelling, restricted range of motion, or systemic signs such as fatigue or unintended weight loss, especially in advanced cases

While some causes are harmless, others may need urgent attention