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El efecto de la citicolina tambin se evalu en un ensayo multicntrico, abierto, y controlado (ensayo IDEALE) en adultos mayores italianos (de 65 a 94 aos) con evidencia de lesiones vasculares en neurorradiologa y dficits cognitivos de leves a moderados, as como evaluado mediante el Mini-Examen del Estado Mental (MMSE

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In addition, aberrant Ca 2+ signaling causing mitochondrial dysfunction can adversely affect neurotransmitter signaling and lead to excitation/inhibition imbalance [94, 97, 98]

Approximately 57 layers of cells were arranged neatly, and regular cell polarity was noted in groups A1, 2 and 3
