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Studies have examined the relationship between NNMT inhibition and cellular NAD+ levels, which are critical for numerous enzymatic reactions including those involving sirtuins and PARPs

Nayana Shetty, MBBS, MD Health Risks Associated with High B12 In some cases, high vitamin B12 levels symptoms can include unusual symptoms like anxiety or a rapid heartbeat, which are more likely associated with the underlying condition, not the elevated B12 levels themselves

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Most side effects are mild and go away quickly