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"Proton Pump Inhibitors, H2-Receptor Antagonists, Metformin, and Vitamin B-12 Deficiency: Clinical Implications"

10.1016/s0753-3322(03)00043-x 49 van ZandwijkN.DalesioO.PastorinoU.De VriesN.Van TinterenH

In contrast, those treated with nab-paclitaxel monotherapy or gemcitabine combined with carboplatin do not exhibit increased OS when pembrolizumab is added

B12 injections (hydroxocobalamin) are available on NHS prescription for treating confirmed vitamin B12 deficiency

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In addition to this, vitamin B12 deficiency in the elderly has been associated with many health problems like elevated blood levels of homocysteine that could increase their chances of developing heart disease, stroke, and Alzheimer's disease