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Therefore, DHODH has emerged as a potential regulatory hub, where its inhibition may enhance ferroptotic cell death, offering a novel angle for therapeutic intervention, particularly in cancers such as pancreatic adenocarcinoma (175) and breast cancer (176), where certain cells show resistance to other forms of cell death (171,177)

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Methionine is a precursor for the polyamines, spermidine and spermine

Adequate folate levels are essential for neurotransmitter synthesis, such as dopamine and serotonin, and regulation of homocysteine levels, the latter linked to neurodegenerative disorders (, )

Antioxidant Protection: It combats free radicals, helping to prevent premature aging and maintaining youthful elasticity