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Respiratory complex II in mitochondrial dysfunction-mediated cytotoxicity: Insight from cadmium

doi: 10.3389/fphar.2023.1067402 127 DAmicoDAndreuxPAValdsPSinghARinschCAuwerxJ

This localized energy failure in muscle and nerve cells is a primary driver of the heavy, leaden fatigue and the severe crashes (PEM) that occur when patients attempt to push past their energetic limits

And it most likely contributes to her remarkably good health and vitality as an older bear

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Cardiovascular protection: CoQ10 supplementation has demonstrated benefits in heart failure, hypertension, and post-surgical recovery