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CTLA-4 blockade increases glucose uptake by Treg cells, promotes IFN production, and destabilizes intratumor Treg cells [148] (Fig
The adaptor protein apoptosis-associated speck-like protein containing CARD (ASC) oligomerizes with inflammasome-forming PRRs, creating a massive cytosol structure that triggers dimerization, autoproteolysis, and pro-caspase-1 zymogen activation (72)
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The ScCas9++ variant expands the CRISPR toolbox for genome editing in plants
Glutathione levels decline with age, stress, pollution, poor diet, and chronic illness
Recent research found that the silent information regulator 1 (SIRT1) autophag y axis in foam cells inhibits excess iron-induced ferroptosis
