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chitinase, glucanase etc.) and PR- -proteins and enhances tolerance against virulent pathogens [167]

Moreover, melatonin may impact amyloid clearance via its impact on insulin-degrading enzyme (IDE), a protease pivotal for catalyzing extracellular and intracellular A degradation [63]

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Nat Commun 13:1989 Liu S, Zhang Y, Zheng X, Wang Z, Wang P, Zhang M, Shen M, Bao Y, Li D (2023a) Sulforaphane inhibits foam cell formation and atherosclerosis via mechanisms involving the modulation of macrophage cholesterol transport and the related phenotype

Impaired methylation leads to a decreased responsiveness of the cell, exactly when it needs it the most when under stress
