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In contrast to PE, chain B of DT, which is on the carboxyl end, is responsible for receptor binding and chain A, which is present on the amino end, contains the enzymatic activity (Uchida et al

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For instance, with the lack of an effective HIV vaccine or weak responses to SARS-CoV-2 vaccines, broadly neutralizing and long-acting anti-HIV and anti-SARS-CoV-2 antibody cocktails may provide a way to prevent or control disease 59,60