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In summary, it can be postulated that during Fe deficiency the accumulation of GSH in cells can activate the vacuolar Fe exporters like AtNRAMP3 and AtNRAMP4 to facilitate Fe export from the vacuolar reserve

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Gain-of-function mutations disrupt this equilibrium by enhancing cation leakage and facilitating the dehydration of RBCs, resulting in hereditary xerocytosis

Florentino GS, Cotrim HP, Vilar CP, Florentino AV, Guimaraes GM, Barreto VS

Moreover, hydrogen has been shown to be effective in alleviating the symptoms of various oxidative stress-related diseases model animals containing UC 9,23,24

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