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The basic mechanisms that regulate systemic iron have been elucidated, and these involve iron-dependent expression of liver hepcidin (Hep) and its interaction with ferroportin (Fpn) (excellent review on this topic in [5, 6]), while mechanisms that regulate brain iron are poorly known

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Unlike traditional biologic DMARDs (which are large proteins administered via injection), targeted synthetic DMARDs (tsDMARDs) are small, synthetic molecules that are taken orally

Mitochondrial complex III is essential for suppressive function of regulatory T cells

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