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Evidence for involvement of N -methylaspartate receptors in wind-up of class 2 neurones in the dorsal horn of the rat

Critically, low doses (approximately 5x baseline levels) were effective while high doses were not, suggesting a therapeutic window

Their dependency on the physiological state of the organism

Statements Data availability statement The original contributions presented in this study are included in the article/Supplementary material, further inquiries can be directed to the corresponding author

Atpenin A5 is a known SDHB inhibitor 52 and was previously assessed for its therapeutic effect on cardiac injury in isolated perfused rat hearts 53

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