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Consistent with earlier reports (Han et al., 2013), analysis of the glutathione-deficient pad2-1 plants demonstrated that 30% of the wild-type glutathione level is enough to sustain ascorbate recycling during high-light exposure

f , Representative bright-field micrographs of Jurkat SLC25A39 knockout cells transduced with the indicated sgRNA at the end of the cell proliferation assay

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In the context of research on HAPH, systems biology can be utilized to map out hypoxic response networks, pinpoint key regulatory elements, and identify potential therapeutic targets