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JAMA Netw Open 7(1):e2350408e2350408 [DOI] [PMC free article] [PubMed] [Google Scholar] Deacon CF (2019) Physiology and pharmacology of DPP-4 in glucose homeostasis and the treatment of type 2 diabetes

Sarcopenia (muscle loss) due to rapid weight loss if measures to preserve muscle are not taken, including regular strength training, staying active, and eating a protein-rich diet

You may be more likely to lose muscle if you: Struggle to meet protein needs Avoid or do not engage in resistance training Experience significant appetite suppression Are you following an unsupervised weight loss approach Are you losing weight rapidly How to Prevent Muscle Loss on GLP-1 Medications Prioritise protein intake Aim for regular protein intake across the day

The most frequently reported side effects, by percent, for GLP-1s, was reported by Liu and colleagues in the journal Frontiers in Endocrinology in December 2022

The extension cohort confirmed it: pushed out to 104 weeks, the curve kept going

Patients whether enrolled in a clinical trial or, in future, receiving retatrutide through a licensed prescriber should be clearly informed of the following red flag symptoms