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These findings provide a mechanistic foundation for developing RNA-based therapeutic interventions (Bao et al., 2020

Crl:CD (SD) rats and cynomolgus monkeys were purchased from Orient Bio Inc

We propose that chronic exposure to a particular suite of environmental and genetic factors elicits a trajectory of impaired mitochondrial biology that maximally impacts subsets of mitotypes abundant in the substantia nigra, striatum, and cerebral cortex, which eventually surfaces as the hallmark features of PD

Zhang H, Reynolds M (2019) Cadmium exposure in living organisms: a short review

L., Broeren, M

When GAS7b was expressed and observed in live cells, the GAS7b patches appeared at ruffled membranes (Fig