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For example, the brain derived neurotrophic factor (BDNF), a neurotrophin highly expressed in the hypothalamus and other brain centers involved in homeostatic regulation of energy balance, seems to ameliorate the diabetic and obese phenotype of LepR deficient mice [52,53,54]
Conte, R., et al
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The mitochondria act as motors inside the cells, burning fat to produce useful energy
Nonetheless, the safe and effective delivery of RNA-based therapeutics is challenging
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