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Description
RP-ILD is defined as worsening dyspnea, hypoxemia, and radiological interstitial changes within 3 months of symptom onset
Based on the annotation files from the Ensembl human genome browser GRCh38, this study performed iterative processing on all genes using Active Perl, extracting the expression matrices for mRNA and lncRNA
A.VaraksinA
A.MlodzianoskiM
There is also the concern of delivery systems due to poor targeting and off-target toxicity
Using proteomics, a recent study identified that this mutation promoted ATP7B interaction with heat shock protein 70 (HSP70), accelerating its degradation in the ER
