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Description
Sample sizes were small and the study has never been replicated at scale, so take it as suggestive, not definitive

Although these differences did not reach statistical significance, they highlight the heterogeneous, region-specific nature of microglial responses, likely influenced by the degree of demyelination and resulting myelin debris, which appeared more pronounced in the corpus callosum and hippocampus when compared to the cortex

85 Shibuya, K

No earlier pharmacologic class has produced double-digit percentage weight reductions sustained over 68 to 88 weeks in large, placebo-controlled cohorts
Beyond changing the readouts on their scales, Brown aims to institute changes in the lifestyles of her clients, from eating a more natural diet to gently hugging themselves every morning.

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