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Description
After an initial cold-like (catarrhal) stage, the patient develops a severe cough which comes in spasms (paroxysms)

Generally safe

Wei et al., mRNA vaccine: a potential therapeutic strategy

[DOI] [PMC free article] [PubMed] [Google Scholar] 15.Hang Y, Wang A and Wu N, Chem

Therefore, it is critical to evaluate PK in a nonclinical model that is thought to best reflect humans, based on anatomic and physiological considerations, and interspecies scaling of the dose can likely benefit most by utilizing a PBPK approach

BMC Psychiatry 24 , 739 (2024)
