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After an initial cold-like (catarrhal) stage, the patient develops a severe cough which comes in spasms (paroxysms)

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Generally safe

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Wei et al., mRNA vaccine: a potential therapeutic strategy

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[DOI] [PMC free article] [PubMed] [Google Scholar] 15.Hang Y, Wang A and Wu N, Chem

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Therefore, it is critical to evaluate PK in a nonclinical model that is thought to best reflect humans, based on anatomic and physiological considerations, and interspecies scaling of the dose can likely benefit most by utilizing a PBPK approach

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BMC Psychiatry 24 , 739 (2024)

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