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AMG 133 (maridebart cafraglutide) is a bispecific molecule engineered by conjugating a fully human monoclonal anti-human GIPR antagonist antibody to two GLP-1 analogue agonist peptides using amino acid linkers

Fogle E

123 Recently, genome-wide association studies (GWAS) have demonstrated that most AD risk genes are highly or exclusively in microglia, 124 suggesting that microglia play an essential role in AD development

10.1038/sj.onc.1204997 [DOI] [PubMed] [Google Scholar] Nagaraju G

In addition, Asia Pacific is projected to increase in the global GLP-1 agonists market because diabetes and other linked illnesses are becoming more common

Tolerability: Fewer GI issues than high-dose GLP-1 RAs