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In a review of studies, researchers found that while vitamin B12 supplementation did not improve depressive symptoms, low vitamin B12 levels were linked to an increased risk of developing depression

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"Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application"

More specialised tests such as active B12 (holotranscobalamin) or methylmalonic acid may be available through specialist referral, though availability varies across the UK

Innovations in Drug Delivery Systems One of the key focuses in 2025 is improving how treatments are delivered to vitiligo-affected skin

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