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Metformin-Induced Vitamin B12 Deficiency Can Cause or Worsen Distal Symmetrical, Autonomic and Cardiac Neuropathy in the Patient With Diabetes

J Immunol 186:18401848 Feng X, Zhang L, Acharya C, An G, Wen K, Qiu L et al (2017) Targeting CD38 suppresses induction and function of T regulatory cells to mitigate immunosuppression in multiple myeloma

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doi:10.1007/s00125-017-4342-z 13

If you are concerned about acne whilst taking B12 supplements, it is advisable to discuss this with your GP rather than discontinuing treatment without medical guidance, particularly if the B12 has been prescribed to address a documented deficiency

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