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doi: 10.1016/j.tcb.2019.05.005

She is not a scientist and thus could not answer any of our technical questions

One recent review concluded that there was no evidence of any benefits of oral supplementation of B12 in diabetic neuropathy (60)

By contrast, your eyelid surgeon may suggest a more mild treatment for dark circles purely caused by hyperpigmentation

However, scientific research shows that very high-dose oral B12 (1,000-2,000 mcg) can be effective for some, as about 1% can be absorbed without intrinsic factor

[DOI] [PubMed] [Google Scholar] 46.Scalabrino G., Corsi M.M., Veber D., Buccellato F.R., Pravettoni G., Manfridi A., Magni P