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Samples were instantly snap-frozen in liquid nitrogen and stored at -80C until analysis [25]

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Thus, the same oxidant, delivered with different timing and intensity, flips transcription from adaptation to pathology (Manuelli et al

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Further development of in vitro modeling should focus on generating precise replicas of the human brains complex structure by combining 3D cell cultures with organoids alongside microfluidic systems containing brain cells such as neurons and astrocytes and microglia to faithfully represent PD pathogenesis [81]

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Ricciardi BR, Saunders JB, Williams R, Hopkinson DA

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However, excessive supplementation may lead to potential and substantial side effects [18]

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Always consult with a doctor if you want to quit the heavy use of alcohol or any medication (especially heart or mental health medications)

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