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PMID: 41255515 Proc Natl Acad Sci U S A Mitochondrial ROS triggers mitophagy through activating the DNA damage response signaling pathway
Graham, Otto M
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Similar to carbon chain lengths, the double bonds in unsaturated fatty acid carbon chains induce conformational changes in PPARs and trigger PPAR-dependent intracellular signals in a manner different from the single bonds in saturated fatty acids [26]
Furthermore, ETC deficiencies are noted in the subunits that are encoded by the mitochondrial DNA, specifically in the ETC Complex III (Poling et al., 2006)
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