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Description
A 90-degree angle, straight into the skin, is appropriate when you can grasp at least 2 inches of tissue in your skin pinch
Studies suggest that various molecular pathways are involved in IC/BPS, including the JUN N-terminal kinase (JNK) pathway, transient receptor potential (TRP) channels, activated mast cells, mucosal signalling, circadian rhythm regulation, inflammation and neural dysregulation
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10.1046/j.1471-4159.1995.64062442.x J
