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doi: 10.1146/annurev.physiol.66.071702.145229 166

A single B12 shot can contain 500 to 1000 mcg or more, going straight into circulation, bypassing the digestive filter

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Current evidence indicates that ROS are major mediators of tissue injury in MS, promoting OS that disrupts the structural and functional integrity of lipids, proteins, and nucleic acids ( Under pathological conditions, OS-induced disruption of the BBB facilitates the infiltration of inflammatory cells into the CNS, where they release cytokines and other mediators that amplify neuroinflammation, creating a self-perpetuating pathological cycle