cagrilintide semaglutide combination phase 3 2024 New in the August 14, 2025, issue of NEJM: Cagrilintide–Semaglutide for Overweight or Obesity (REDEFINE 1 3a trial) https://nej.md/444aW7f Cagrilintide–Semaglutide for Overweight and Diabetes (REDEFINE 2 phase 3a trial) https://nej.md/4ehQwLk Incretin-based therapies for the treatment

Subcision can be done in superficial or deep fashion. Shallow scars may only require subcision into the depth whereas deeper scars such as rolling scars may need to have subcision deeper into the subdermal level due to fibrous anchoring to the subcutis [5]

Gentle swirling is used if needed

The deltoid is easily accessible without needing to undress the patient extensively, making it a convenient site for quick and effective injections, especially in outpatient settings

Luger TA, et al

doi:10.1007/s00198-007-0520-z Arlt W, Callies F, Koehler I, et al

Angiogenesis and nutrient delivery Vascular network importance: Healing tissues require increased metabolic support (oxygen, glucose, amino acids, minerals)